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Lipid and Carbohydrate Metabolism in Indigenous and Caucasian Young Males Living in the Magadan Region. P. 5–15

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Section: Physiology

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Authors

Inessa V. Averyanova
Scientific Research Centre “Arktika”, Far Eastern Branch of the Russian Academy of Sciences
24 prosp. Karla Marksa, Magadan, 685000, Russian Federation;
e-mail: Inessa1382@mail.ru
Arkady L. Maksimov
Scientific Research Centre “Arktika”, Far Eastern Branch of the Russian Academy of Sciences
24 prosp. Karla Marksa, Magadan, 685000, Russian Federation;
e-mail: arkmax@mail.ru
Nikolay S. Borisenko
Scientific Research Centre “Arktika”, Far Eastern Branch of the Russian Academy of Sciences
24 prosp. Karla Marksa, Magadan, 685000, Russian Federation;
e-mail: arkmax@mail.ru

Abstract

We studied the lipid spectrum and blood glucose in 17–21-year-old indigenous males (Evens, Koryaks, and Chukchi) compared to those of first- and second-generation Caucasian natives of the Magadan Region. The results showed that the lipid profile in these groups stayed within the reference values, approaching, however, the lower limit of normal. This can be associated with lower consumption of fats and their replacement by carbohydrates. We observed statistically significant differences in a number of average lipid profile values between the indigenous and native Caucasian populations. The level of low density lipoprotein (“bad cholesterol”) in Caucasians was statistically higher than that in indigenous males, accounting for a higher atherogenic coefficient in Caucasians. An individual analysis of variations within the values under study revealed the largest proportion of lipid metabolism deviation (from the accepted norm) among Caucasians, whereas the indigenous group demonstrated practically no signs of it. Blood glucose values in both groups were approaching the upper limit of normal, with 5.6 mmol/L or higher in 25–28 % of the subjects. The elevated levels of blood glucose found in many Magadan students indicate an emerging prediabetis and allow us to place them in a risk group for persistent carbohydrate metabolism disorder.

Keywords

Magadan Region, indigenous peoples, native Caucasians, lipid metabolism, carbohydrate metabolism, dietary changes, lifestyle

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