UDC

612.824

DOI

10.17238/issn2542-1298.2019.7.1.5

Authors

Nadezhda L. Guseva*, Nikolay B. Suvorov*, Tat’yana V. Pryanishnikova*
*Institute of Experimental Medicine (St. Petersburg, Russian Federation)

Abstract

The research aimed to study blood and cerebrospinal fluid (CSF) flow dynamics in the human brain according to electroencephalogram (EEG) patterns under oscillatory postural loads in the form of passive periodic antiorthostatic head-down tilts of –15°. EEG was recorded continuously by a wireless 21-channel encephalograph. We surveyed 23 subjects aged between 19 and 24 years. Their blood and CSF flow dynamics was evaluated by EEG patterns using a method having high diagnostic accuracy (patent no. 2436503 of 20.12.2011). According to this method, the ratio of mean theta power in the frontal EEG leads (Fp1, Fpz, Fp2, Fz) to that in the parietal EEG leads (P1, Pz, P2) is determined by the coefficient of blood and CSF flow dynamics (Cd), whose normal value is 1.2 or less. Heightened Cd value indicates either disturbed blood and CSF flow dynamics in the brain or intracranial hypertension. Six subjects with signs of disturbed blood and CSF flow dynamics in the brain identified during preliminary examination (Cd > 1.2), under postural loads showed either a decrease in the severity of these symptoms or normalization of blood and CSF flow dynamics according to Cd. In the remaining 17 subjects, blood and CSF flow dynamics under postural loads stayed within the normal range. The results allow us to conclude that postural loads in the form of passive periodic antiorthostatic head-down tilts of –15° produce a beneficial effect on cerebral circulation, normalize blood and CSF flow dynamics and do not affect it if it is normal.

Keywords

postural loads, blood and CSF flow dynamics, electroencephalogram, antiorthostasis

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