UDC

612.171.1 :613.8

DOI

10.17238/issn2542-1298.2019.7.3.318

Authors

Oksana S. Preminina*, Tat’yana S. Mityagina*
*Northern (Arctic) Federal University named after M.V. Lomonosov (Arkhangelsk, Russian Federation)
Corresponding author: Oksana Preminina, address: ul. Severodvinskaya 13, korp. 1, Arkhangelsk, 163000, Russian Federation; e-mail: dr.bronco@mail.ru

Abstract

This article explores the important topic of psychoactive substance use among adolescents. Volatile solvents in household chemicals pose a great danger to child health. Inhalant vapours penetrate deeply into the respiratory tract and are then quickly absorbed by the body. These substances transform the structure of biological membranes and change their functional status. Structural elements of the intercellular space and those of cells become targets for toxicants. Their toxic influence leads to disorders of haemodynamics, the respiratory system, autonomic processes, as well as metabolism in organs and tissues. Heart rate variability reflects the functioning of the cardiovascular system and regulation processes in the body as a whole. With the help of a comprehensive research into heart rate variability, the authors assessed the influence of psychoactive substances on the cardiovascular system of adolescents living in the European North of Russia. We found that volatile solvents produce a significant effect on the functional state of the cardiovascular system. In particular, adolescents using toxicants showed a delay in the maturation of brain structures, as well as greater stress of central haemodynamic mechanisms. Moreover, the results of the study point out an increase in absolute temporal and spectral indicators of heart rate variability in adolescents as they continue using volatile solvents over time. The findings are of great value to environmental and developmental physiology and can form the basis for further research in this area.

Keywords

adolescents, volatile solvents, heart rate variability

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