UDC

[612.17:616.24:616-07]-053.67

DOI

10.37482/2687-1491-Z265

Authors

Liliya V. Poskotinova* ORCID: https://orcid.org/0000-0002-7537-0837
Anna V. Ukhanova* ORCID: https://orcid.org/0000-0001-9083-9931
*N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences (Arkhangelsk, Russia)

Corresponding author: Liliya Poskotinova, address: prosp. Nikol’skiy 20, Arkhangelsk, 163029, Russia; e-mail: liliya200572@mail.ru

Abstract

Slow-paced breathing (SPB) test at 6 respiratory cycles per minute is used to identify reduced vagal regulation of the cardiorespiratory system. However, no standard variation range of cardiac intervals during this test in young residents of the Arctic aged 16–18 years has been established. The purpose of this study was to determine the percentile ranges of the variation of cardiac intervals (MxRMn) as well as of time-domain and spectral heart rate variability (HRV) parameters during SPB in 16- to 18-year-olds living in the northern part of the Arkhangelsk Region. Materials and methods. The study involved 253 healthy male and female subjects aged 16–18 years living in the Arctic areas (and those equated thereto) of the Arkhangelsk Region. Their HRV parameters were recorded at baseline (5 minutes) and during SPB (5 minutes) using Varikard equipment (Ramena, Russia). MxRMn percentiles (p10, p25, p75, p90), blood pressure and HRV parameters were determined and controlled for sex. Results. During SPB in male subjects, MxRMn median and p10–p90 range were significantly higher (1.75 [1.49; 2.06] ms) compared to those in female subjects (1.69 [1.45; 1.98] ms, p < 0.05). These values were accompanied by a greater increase in HRV parameters reflecting vagal regulation and by a smaller increase in the low-frequency HRV component in males compared to females (p < 0.05). A decrease in the MxRMn parameter during SPB below 1.49 ms in young men and below 1.45 ms in young women aged 16–18 years reflects a risk of dysfunction in the autonomic regulation of the cardiorespiratory system. Normative intervals of MxRMn values for individuals aged 16–18 years were proposed.

Funding. The research was carried out within the framework of the state assignment of N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences No. 125022002730-2.

Keywords

heart rate variability, slow-paced breathing, young population of the Arkhangelsk Region, Arctic zone of the Russian Federation, adaptive reactions, polar stress syndrome, oxidative stress, cardiovascular disease, normal variation range of cardiac interva

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