UDC

612.82:[612.13+611.81]

DOI

10.37482/2687-1491-Z144

Authors

Petr A. Prodius*/**/*** ORCID: https://orcid.org/0000-0002-1106-120X
Aleksey E. Bazhenov* ORCID: https://orcid.org/0000-0003-2397-9904
Mariya D. Berstneva* ORCID: https://orcid.org/0000-0002-8798-6954

*National Research Lobachevsky State University of Nizhny Novgorod (Nizhny Novgorod, Russian Federation)
**Privolzhsky Research Medical University (Nizhny Novgorod, Russian Federation)
***Nizhny Novgorod State Agricultural Academy (Nizhny Novgorod, Russian Federation)

Corresponding author: Petr Prodius,
address: prosp. Gagarina 25, korp. 1, Nizhny Novgorod, 603950, Russian Federation;
e-mail: prodiusnn@yandex.ru

Abstract

The purpose of this paper was to study the relationship between cerebral circulation during shortterm mental load and the efficiency of behaviour control. Previous studies failed to provide a clear picture of the functional restructuring of cerebral circulation in response to mental activity. One of the reasons for the ambiguity of their results may be individual differences. This is confirmed by the existing typological differences in cerebral circulation at rest and in response to mental load. In this study, we highlighted another potential typological feature, namely, bilateral asymmetry of cerebral circulation in the internal carotid arteries. The available data suggest that the asymmetry of cerebral circulation is linked with the productivity of mental activity and the efficiency of behaviour control. Materials and methods. Rheoencephalography was used to study the parameters of cerebral circulation in 20 students (aged 19–23 years) during mental load (Go/No-Go test). The stimuli were presented on a monitor using the PsychoPy program. The reaction time and the number of errors were evaluated. Rheoencephalograms were recorded using the Reo-Spektr rheoencephalograph. Pulse volume at rest and during mental load in the internal carotid arteries was assessed according to the amplitude-frequency index (AFI). Blood flow asymmetry in the frontal regions was assessed using the asymmetry coefficient. Results. Under short-term mental load in students, a tendency towards a moderate increase in pulse volume in the frontal regions was observed. A negative correlation was established between the AFI in the right frontal region and the number of errors in the Go/No-Go test. The research into the relationship between blood flow asymmetry in the internal carotid arteries and execution accuracy of the Go/No-Go test revealed a positive correlation between the predominance of blood circulation in the left frontal area and test execution accuracy. Prospects for using the asymmetry of cerebral circulation in the internal carotid arteries to predict mental activity efficiency are discussed.

Keywords

rheoencephalography, short-term mental load, Go/No-Go, cerebral circulation, internal carotid arteries, adaptation to mental load, behaviour control, functional brain asymmetry

References

1. Yarullin Kh.Kh. Klinicheskaya reoentsеfalografiya [Clinical Rheoencephalography]. Moscow, 1983. 270 p.
2. Poskotinova L.V., Kamenchenko E.A. Pokazateli reoentsefalogrammy pokoya u zdorovykh podrostkov 15–17 let na Evropeyskom Severe [Quiet Rheoencephalogram Indicators in Healthy Adolescents Aged 15–17 Years in European North]. Ekologiya cheloveka, 2011, no. 9, pp. 36–44.
3. Peshev L.P., Tumaeva Yu.A., Lyalichkina N.A. Biorezonansnaya korrektsiya rasstroystv vegetativnogo gomeostaza u zhenshchin-operatorov personal’nykh komp’yuterov [Bioresonance Correction Disorders of Vegetative Homeostasis of Women Operators of Personal Computers]. Fundamental’nye issledovaniya, 2013, no. 9-3, pp. 440–443.
4. Wei W., Li Y., Xie Z., Deegan A.J., Wang R.K. Spatial and Temporal Heterogeneities of Capillary Hemodynamics and Its Functional Coupling During Neural Activation. IEEE Trans. Med. Imaging, 2018, vol. 38, no. 5, pp. 1295–1303. DOI: 10.1109/TMI.2018.2883244
5. Mel’nik S.N., Mel’nik V.A., Sukach E.S., Tkachenko P.V. Vliyanie fizicheskoy i umstvennoy nagruzki na sostoyanie tsentral’noy i mozgovoy gemodinamiki molodykh lyudey v zavisimosti ot tipa krovoobrashcheniya i tserebral’noy mikrotsirkulyatsii [The Impact of Physical Exercise and Mental Load on the State of the Central and Cerebral Hemodynamics of Young People Depending on the Type of Blood Circulation and Cerebral Microcirculation]. Kurskiy nauchno-prakticheskiy vestnik “Chelovek i ego zdorov’e”, 2016, no. 1, pp. 117–123.
6. Chub I.S., Boreyko A.P., Kunavin M.A., Cherkasova A.S., Preminina O.S. Osobennosti mozgovoy gemodinamiki u studentov v protsesse vypolneniya kognitivnoy zadachi [Features of Cerebral Hemodynamics in Students in the Process of Performing a Cognitive Task]. Mezhdunarodnyy zhurnal prikladnykh i fundamental’nykh issledovaniy, 2021, no. 2, pp. 16–20.
7. Sharapov A.N., Sel’verova N.B., Dogadkina S.B., Kmit’ G.V., Rubleva L.V., Bezobrazova V.N., Ermakova I.V. Funktsional’noe sostoyanie serdechno-sosudistoy i endokrinnoy sistem u podrostkov 15-16 let [Functional State of the Cardiovascular and Endocrine Systems in 15–16-Year-Old Adolescents]. Novye issledovaniya, 2018, no. 3-4, pp. 39–60.
8. Mandrikov V.B., Sevryukova G.A., Isupov I.B., Likhodeeva V.A. Tserebral’noe krovoobrashchenie rossiyskikh i inostrannykh studentov pri razlichnykh formakh umstvennoy deyatel’nosti [Cerebral Circulation of Russian and Foreign Students in Various Forms of Mental Activity]. Vestnik Volgogradskogo gosudarstvennogo meditsinskogo universiteta, 2019, no. 1, pp. 87–90.
9. Markhasina I.P. Rheoencephalographic Study of the Hemodynamics During Mental Work. Bull. Exp. Biol. Med., 1970, vol. 70, no. 6, pp. 1355–1357. DOI: 10.1007/BF02066772
10. Isupov I.B., Zankovich A.A., Kochubeeva E.N. Tipologicheskie osobennosti krovoobrashcheniya golovnogo mozga molodykh lyudey [Typological Features of Cerebral Circulation in Young People]. Vestnik Volgogradskogo gosudarstvennogo universiteta. Ser. 7: Filosofiya. Sotsiologiya i sotsial’nye tekhnologii, 2008, no. 1, pp. 124–129.
11. Ponomareva T.A. Osobennosti adaptatsii sistemy perifericheskogo krovoobrashcheniya k operatorskoy deyatel’nosti u detey 8–10 let s raznymi tipami avtonomnoy nervnoy regulyatsii [Peripheral Circulatory System Adaptation to Operator Activity in 8–10-Year-Old Children with Different Types of Autonomic Nervous Regulation]. Novye issledovaniya, 2004, no. 1–2, p. 316.
12. Bezobrazova V.N. Kratkosrochnaya adaptatsiya mozgovogo krovoobrashcheniya k umstvennoy nagruzke u detey 7-8 let [Short-Term Adaptation of Cerebral Circulation to Mental Work in 7–8-Year-Old Children]. Novye issledovaniya, 2011, no. 2, pp. 90–95.
13. Adamovskaya O.N., Orlov K.V., Bezobrazova V.N. Izmeneniya tserebral’nogo krovotoka u detey 8-9 let pri vypolnenii umstvennoy nagruzki na raznykh elektronnykh ustroystvakh [Changes in Cerebral Blood Circulation in 8–9-Year-Old Children Using Different Electronic Devices to Mental Tasks]. Novye issledovaniya, 2020, no. 2, pp. 5–14.
14. Jacquy J., Noel P., Segers A., Huvelle R., Piraux A., Noel G. Regional Cerebral Blood Flow in Children. A Rheoencephalographic Study of the Modifications Induced by Reading. Electroencephalogr. Clin. Neurophysiol., 1977, vol. 42, no. 6, pp. 691–696. DOI: 10.1016/0013-4694(77)90285-1
15. Zaripov V.N., Barinova M.O. Gemodinamicheskie izmeneniya tserebral’nogo krovotoka pod vliyaniem umstvennoy nagruzki u studentok s raznym tipom temperamenta [Cerebral Hemodynamics Changes of Girls-Students with Different Type of Temperament Under the Influence of Intellectual Loadings of Various Intensity]. Vestnik Ivanovskogo gosudarstvennogo universiteta. Ser.: Estestvennye, obshchestvennye nauki, 2012, no. 2, pp. 14–22.
16. Olenko E.S., Yupatov V.D., Fomina E.V., Kodochigova A.I., Konovalova A.A. Dependence of Passivity and Activity of Behavior on the Condition of the Brain Blood of Healthy Men. Psychosom. Integr. Res., 2019, vol. 5, no. 3, p. 305 (in Russ.).
17. Adler L.A., Faraone S.V., Spencer T.J., Berglund P., Alperin S., Kessler R.C. The Structure of Adult ADHD. Int. J. Methods Psychiatr. Res., 2017, vol. 26, no. 1, pp. 15–55. Art. no. e1555. DOI: 10.1002/mpr.1555
18. Bron T.I., Bijlenga D., Breuk M., Michielsen M., Beekman A.T.F., Kooij J.J.S. Risk Factors for Adverse Driving Outcomes in Dutch Adults with ADHD and Controls. Accid. Anal. Prev., 2018, vol. 111, pp. 338–344. DOI: 10.1016/j.aap.2017.12.011
19. Gribanov A.V., Mel’kova L.A., Startseva L.F. Mozgovaya gemodinamika u giperaktivnykh detey s defitsitom vnimaniya [Cerebral Hemodynamics in Children with Attention Deficit Hyperactivity Disorder]. Ekologiya cheloveka, 2013, no. 10, pp. 49–54.
20. Monden Y., Dan H., Nagashima M., Dan I., Kyutoku Y., Okamoto M., Yamagata T., Momoi M.Y., Watanabe E. Clinically-Oriented Monitoring of Acute Effects of Methylphenidate on Cerebral Hemodynamics in ADHD Children Using fNIRS. Clin. Neurophysiol., 2012, vol. 123, no. 6, pp. 1147–1157. DOI: 10.1016/j.clinph.2011.10.006
21. Kaga Y., Ueda R., Tanaka M., Kita Y., Suzuki K., Okumura Y., Egashira Y., Shirakawa Y., Mitsuhashi S., Kitamura Y., Nakagawa E., Yamashita Y., Inagaki M. Executive Dysfunction in Medication-Naïve Children with ADHD: A Multi-Modal fNIRS and EEG Study. Brain Dev., 2020, vol. 42. no. 8, pp. 555–563. DOI: 10.1016/j.braindev.2020.05.007
22. Gomez P., Ratcliff R., Perea M. A Model of the Go/No-Go Task. J. Exp. Psychol. Gen., 2007, vol. 136, no. 3, pp. 389–413. DOI: 10.1037/0096-3445.136.3.389
23. Peirce J., MacAskill M. Building Experiments in PsychoPy. London, 2018. 312 p.
24. Kompleks reograficheskiy “Reo-Spektr”. Metodicheskie ukazaniya [Rheographic Complex “Reo-Spektr”. Guidelines]. Ivanovo, 2008. 142 p.
25. Prodius P.A. Neyrofiziologicheskie markery kontrolya povedeniya v paradigmakh go/nogo i novel [Neurophysiological Markers of Behaviour Control in the Go/No-Go and Novel Paradigms]. Trudy Pyatoy Vserossiyskoy konferentsii “Nelineynaya dinamika v kognitivnykh issledovaniyakh – 2017” [Proceedings of the 5th All-Russian Conference “Nonlinear Dynamics in Cognitive Research – 2017”]. Nizhny Novgorod, 2017, pp. 176–178.
26. Butler S.R., Glass A. Asymmetries in the Electroencephalogram Associated with Cerebral Dominance. Electroencephalogr. Clin. Neurophysiol., 1974, vol. 36, no. 5, pp. 481–492. DOI: 10.1016/0013-4694(74)90205-3
27. Pankov M.N., Afanasenkova N.V., Kozhevnikova I.S., Podoplekin A.N. Sostoyanie neyroenergometabolizma u detey s sindromom defitsita vnimaniya s giperaktivnost’yu i emotsional’nymi rasstroystvami [State of Neuroenergometabolism in Children with Attention Deficit Hyperactivity Disorder and Emotional Disorders]. Mezhdunarodnyy zhurnal prikladnykh i fundamantal’nykh issledovaniy, 2016, no. 9-1, pp. 66–69.
28. Pankov M.N., Kozhevnikova I.S., Sidorova E.Yu., Gribanov A.V., Startseva L.F. Psychophysiological Characteristics of Children with Aggressive Behavior. Ekologiya cheloveka, 2018, no. 2, pp. 37–44. DOI: 10.33396/1728-0869-2018-2-37-44
29. Hale T.S., Smalley S.L., Dang J., Hanada G., Macion J., McCracken J.T., McGough J.J., Loo S.K. ADHD Familial Loading and Abnormal EEG Alpha Asymmetry in Children with ADHD. J. Psychiatr. Res., 2010, vol. 44, no. 9, pp. 605–615. DOI: 10.1016/j.jpsychires.2009.11.012
30. Lutsenko E.L. Osobennosti mezhpolusharnoy asimmetrii indeksa al’fa-ritma u studentov [Interhemispheric Asymmetry of the Alpha Rhythm Index in Students]. Vestnik psikhofiziologii, 2013, no. 2, pp. 34–40.
31. Lebedeva N.N., Karimova E.D. Neyrofiziologicheskie proyavleniya sostoyaniya monotonii u operatorov s razlichnoy mezhpolusharnoy asimmetriey al’fa-aktivnosti [Neurophysiological Manifestations of the Monotony State in the Human-Operators with Different Alpha-Activity Hemispheric Asymmetry]. Zhurnal vysshey nervnoy deyatel’nosti im. I.P. Pavlova, 2014, vol. 64, no. 4, pp. 428–438. DOI: 10.7868/S0044467714040108