CC..png    

16plus.png

Legal and postal addresses of the founder and publisher: Northern (Arctic) Federal University named after M.V. Lomonosov, Naberezhnaya Severnoy Dviny, 17, Arkhangelsk, 163002, Russian Federation

Editorial office address: Journal of Medical and Biological Research, 56 ul. Uritskogo, Arkhangelsk

Phone: (818-2) 21-61-00, ext.18-20

E-mail: vestnik_med@narfu.ru
https://vestnikmed.ru/en/

ABOUT JOURNAL

Molecular Genetic and Biochemical Markers for Assessing Physical Abilities of Athletes. C. 195-204

Версия для печати

Section: Clinical medicine

Download (pdf, 0.5MB )

UDC

796.015.682:613.735

DOI

10.37482/2687-1491-Z241

Authors

Olga V. Zinchenko* ORCID: https://orcid.org/0009-0008-4321-0039
Valeriy A. Antonov* ORCID: https://orcid.org/0000-0001-6435-4316
Dmitriy S. Sharonov* ORCID: https://orcid.org/0009-0009-0933-5863
Yuliya I. Kochkalda* ORCID: https://orcid.org/0009-0005-9139-6294
Galina A. Ivanenko* ORCID: https://orcid.org/0009-0002-7809-9373
Viktoriya A. Pak* ORCID: https://orcid.org/0000-0003-1799-5211
Nikolay N. Sentyabrev** ORCID: https://orcid.org/0000-0001-5253-7078
Aleksey G. Kamchatnikov** ORCID: https://orcid.org/0000-0002-5068-467X

*Research Institute of Hygiene, Toxicology and Occupational Pathology
(Volgograd, Russia)
**Volgograd State Physical Education Academy
(Volgograd, Russia)

Abstract

Studying athletes’ genetic and biochemical markers allows us to monitor physiological changes and adjust training cycles to improve training efficiency and minimize fatigue. The purpose of this article is to investigate the relationship between biochemical parameters and polymorphic variants of genes and assess an athlete’s predisposition to certain specialities. Materials and methods. The research involved 22 students from Volgograd State Physical Education Academy aged 16–23 years and doing athletics (n = 22, mean age 19.5 years, length of training 6–10 years, average training frequency 5–7 three-hour sessions a week). The biochemical parameters of blood serum were analysed using the Selectra ProM system (Vital Scientific B.V., Elitech Holding, the Netherlands) with reagent kits from Analyticon (Germany). Genetic markers were studied using the commercial DNA isolation kit Proba-GS-Genetika (DNA-Technology, Russia) and the PCR test system Sports Genetics (Lytech, Russia). Real-time amplification was carried out on a CFX96 Touch Real-Time PCR Detection System (Bio-Rad, USA) in microcentrifuge tubes (0.2 ml) using hot start. Results. According to the cluster analysis of the identified genetic polymorphisms, the examined athletes were divided into two groups: stayers and sprinters. No clear groups could be singled out based on the biochemical analysis. Moreover, no correlation was established between the presence of genes responsible for speed, strength and endurance and blood biochemistry.

Keywords

personalized approach to sports training, sports medicine, gene polymorphism, biochemical tests, sports specialization, physical abilities of athletes

References

  1. Konradi A.O. Biomarkers, Types and Role in Personalized Medicine. Russ. J. Personalized Med., 2022, vol. 2, no. 3, pp. 6–16 (in Russ.). https://doi.org/10.18705/2782-3806-2022-2-3-6-16
  2. Gavrilova S.O. Personalizirovannyy podkhod v obosnovanii referentnykh intervalov biokhimicheskikh markerov peretrenirovannosti na primere grebtsov-akademistov [Personalized Approach in Substantiation of Reference Intervals of Biochemical Markers of Overtraining on the Example of Rowers]. Prikladnaya sportivnaya nauka, 2022, no. 1, pp. 71–79.
  3. Huang M., Chen W., Nakamura T., Kimura Y. Editorial: Discovery of Digital Biomarkers in the Background of Big Data and Advanced Machine Learning. Front. Physiol., 2023, vol. 14. Art. no. 1239219. https://doi.org/10.3389/fphys.2023.1239219
  4. Lee E.C., Fragala M.S., Kavouras S.A., Queen R.M., Pryor J.L., Casa D.J. Biomarkers in Sports and Exercise: Tracking Health, Performance, and Recovery in Athletes. J. Strength Cond. Res., 2017, vol. 31, no. 10, pp. 2920–2937. https://doi.org/10.1519/JSC.0000000000002122
  5. Haller N., Behringer M., Reichel Т., Wahl P., Simon P., Krüger K., Zimmer P., Stöggl T. Blood-Based Biomarkers for Managing Workload in Athletes: Considerations and Recommendations for Evidence-Based Use of Established Biomarkers. Sports Med., 2023, vol. 53, no. 7, pp. 1315–1333. https://doi.org/10.1007/s40279-023-01836-x
  6. Shibkova D.Z., Bayguzhin P.A., Erlikh V.V., Batueva A.E., Sabir’yanova E.S. Otbor i mediko-biologicheskoe soprovozhdenie odarennykh obuchayushchikhsya, realizuyushchikh obrazovatel’nuyu i sportivnuyu deyatel’nost’ [Selection and Biomedical Support for Gifted Children Simultaneously Involved in Education and Sports]. Sci. Educ. Today, 2020, vol. 10, no. 5, pp. 196–210. https://doi.org/10.15293/2658-6762.2005.11
  7. Ponomareva O.V. Genetics in Modern Sports: Scientific Technologies for New Achievements. Eruditio Juvenium, 2018, vol. 6, no. 4, pp. 569–581 (in Russ.). https://doi.org/10.23888/HMJ201864569-581
  8. Imanbekova M.K., Zholdybaeva E.V., Esentaev T.K., Momynaliev K.T. Sport i genetika [Sports and Genetics]. Biotekhnologiya. Teoriya i praktika, 2013, no. 2, pp. 4–11.
  9. Shamsuvaleeva E.Sh., Nevmyvaka A.I., Nazarenko A.S. Challenges of Interpretation of Genetic Test Results on the Example of Study of Endurance. Sci. Sport Curr. Trends, 2019, vol. 8, no. 1, pp. 75–82 (in Russ.).
  10. Buxens A., Ruiz J.R., Arteta D., Artieda M., Santiago C., González-Freire M., Martínez A., Tejedor D., Lao J.I., Gómez-Gallego F., Lucia A. Can We Predict Top-Level Sports Performance in Power vs Endurance Events? A Genetic Approach. Scand. J. Med. Sci. Sports, 2011, vol. 21, no. 4, pp. 570–579. https://doi.org/10.1111/j.1600-0838.2009.01079.x



Make a Submission


INDEXED IN: 

DOAJ_logo-colour.png

Elibrary.ru

logotype.png

infobaseindex

Логотип.png




Лань

OTHER NArFU JOURNALS: 

Vestnik of NArFU.
Series "Humanitarian and Social Sciences"

Forest Journal 
obl_les2023.jpg 

Arctic and North  

AiS.jpg

Продолжая просмотр сайта, я соглашаюсь с использованием файлов cookie владельцем сайта в соответствии с Политикой в отношении файлов cookie, в том числе на передачу данных, указанных в Политике, третьим лицам (статистическим службам сети Интернет).