UDC

616.8-009.29-06:616.89-008.47

Authors

Chutko Leonid Semenovich, Institute of Human Brain, Russian Academy of Sciences (St. Petersburg, Russia)

Surushkina Svetlana Yuryevna, Institute of Human Brain, Russian Academy of Sciences; Faculty for Clinical Psychology, Saint-Petersburg State Pediatric Medical University (St. Petersburg, Russia)

Yakovenko Elena Aleksandrovna, Institute of Human Brain, Russian Academy of Sciences (St. Petersburg, Russia)

Nikishena Inna Sergeevna, Institute of Human Brain, Russian Academy of Sciences; Faculty for Clinical Psychology, Saint-Petersburg State Pediatric Medical University (St. Petersburg, Russia)

Anisimova Tatyana Igorevna, Institute of Human Brain, Russian Academy of Sciences; Faculty for Clinical Psychology, Saint-Petersburg State Pediatric Medical University (St. Petersburg, Russia)

Bykova Yuliya Leonidovna, Institute of Human Brain, Russian Academy of Sciences (St. Petersburg, Russia)

Sergeev Aleksandr Viktorovich, Institute of Human Brain, Russian Academy of Sciences (St. Petersburg, Russia)

Abstract

Functional brain activity in 162 children with tics has been studied. Children with chronic tics had significantly greater degree of impulsivity and inattention than children with transient tics. Comparative analysis of EEG power spectra in children with chronic tics showed lower values of alpha rhythm intensity in the occipital leads and greater values of ratio of theta- and beta-1 rhythms as compared to healthy children and children with transient tics.

Keywords

children, hyperkinesis, clinical and physiological characteristics.

References

1. Zykov V.P. Tiki detskogo vozrasta [Childhood tics]. Moscow, Antidor Publ., 2002. 180 p.
2. Zykov V.P., Shiretorova D.Ch., Shadrin V.N., Chuchin M.Yu., Komarova I.B., Milovanova O.A., Begasheva O.I., Mazankova L.N., Kurenkov A.L., Nikitin S.S. Diagnostika i lechenie bolezney nervnoy sistemy u detey [Diagnosis and Treatment of Neurological Disorders in Children]. Moscow, Triada-Kh Publ., 2006. 256 p.
3. Levin O.S. Tikoznye giperkinezy [Tic disorders]. Ekstrapiramidnye rasstroystva: rukovodstvo po diagnostike i lecheniyu [Extrapyramidal Disorders: a Guide to Diagnosis and Treatment]. Moscow, 2002, pp. 313–356.
4. Njiokiktjien Ch. Detskaya povedencheskaya nevrologiya [Pediatric Behavioural Neurology], vol. 2. Moscow, Terevinf Publ., 2010, 336 p.
5. Sukhotina N.K., Kryzhanovskaya I.L., Konovalova V.V., Kupriyanova T.A. Opyt primeneniya nootropov pri pogranichnykh psikhicheskikh rasstroystvakh u detey [The Experience of Using Nootropics for Treatment of Children with Borderline Mental Disorders]. Psikhiatriya i psikhofarmakoterapiya, 2004, no. 6, pp. 298–301.
6. Chutko L.S. Sindrom defitsita vnimaniya s giperaktivnost’yu i soputstvuyushchie rasstroystva [Attention Deficit Hyperactivity Disorder and Related Disorders]. St. Petersburg, Khoka Publ., 2007. 136 p.
7. Shan’ko G.G. Tiki [Tics]. Nevrologiya detskogo vozrasta: vospalitel’nye i nasledstvennye zabolevaniya, somatonevrologicheskie sindromy, nevrozy i nevrozopodobnye sostoyaniya [Pediatric Neurology: Inflammatory and Hereditary Diseases, Somatic and Neurological Syndromes, Neuroses and Neurosis-like Conditions]. Minsk, 1990, pp. 454–463.
8. Cavanna A.E., Eddy C., Rickards H.E. Cognitive Functioning in Tourette Sindrome. Discov. Med., 2009, vol. 8, no. 43, pp. 191–195.
9. Jankovic J. Tourette’s Syndrome. N. Engl. J. Med., 2001, vol. 345, pp.1184–1192.
10. Khalifa N., von Knorring A. Prevalence of Tic Disorders and Tourette Syndrome in a Swedish School Population. Developmental Medicine & Child Neurology, 2003, vol. 45, pp. 315–319.
11. Knell E.R., Comings D.E. Tourette’s syndrome and attention-deficit hyperactivity disorder: evidence for a genetic relationship. J. Clin. Psychiatry, 1993, vol. 54, no. 9, pp. 331–337.
12. Kurlan R. Clinical practice. Tourette’s Syndrome. N. Engl. J. Med., 2010, vol. 363, no. 24, pp. 2332–2338.
13. J.M. Scharf, L.L. Miller, C.A. Mathews, Y. Ben-Shlomo. Prevalence of Tourette Syndrome and Chronic Tics in the Population-based Avon Longitudinal Study of Parents and Children Cohort. J. Am. Acad. Child. Adolesc. Psychiatry., 2012, vol. 51, no. 2, pp.192–201.
14. J.C. Du, T.F. Chiu, K.M. Lee, H.L. Wu et al. Tourette syndrome in children: an updated review. Pediatr. Neonatol., 2010, vol. 51, no. 5, pp. 255–264.
15. Shapiro A.К., Shapiro Е.К. Tic Disorders. J. Am. Med. Assoc., 1981, vol. 245, pp. 1583–1585.